Together, our data elucidate key factors and mechanisms involved in colorectal cancer liver metastasis, which could be potential targets for diagnosis and treatment.
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B Representative images of protein expression levels of 4 genes in nonmetastatic human colorectal cancer samples and human colorectal cancer with hepatic metastases using immunohistochemistry staining.
A Protein expression levels of 4 genes were detected by immunoblotting in nonmetastatic human colorectal cancer samples and human colorectal cancer samples with hepatic metastases.
Currently, the genes and molecular mechanisms that are functionally critical in modulating colorectal cancer hepatic metastasis remain unclear.